Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Caenorhabditis elegans as a model to study renal development and disease: sexy cilia.

Journal of the American Society of Nephrology : JASN - 1 Feb 2005

Barr Maureen M

Abstract excerpt

The nematode Caenorhabditis elegans has no kidney per se, yet "the worm" has proved to be an excellent model to study renal-related issues, including tubulogenesis of the excretory canal, membrane transport and ion channel function, and human genetic diseases including autosomal dominant polycystic kidney disease (ADPKD). The goal of this review is to explain how C. elegans has provided insight into cilia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins
Share to Cilia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Helminth Proteins

Share to Models, Animal

Share to Organogenesis

Share to Polycystic Kidney, Autosomal Dominant

Share to Polycystic Kidney, Autosomal Recessive

Source

Identifiers

PMID: 15647338
DOI: 10.1681/ASN.2004080645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Caenorhabditis elegans as a model to study renal development and disease: sexy cilia.PMID 15647338Read ↗

Caenorhabditis elegans, a model organism for kidney research: from cilia to mechanosensation and longevity.Semantic proximity Read ↗

Antennas of organ morphogenesis: the roles of cilia in vertebrate kidney developmentSemantic proximity Read ↗

Mating worms and the cystic kidney: Caenorhabditis elegans as a model for renal disease.Semantic proximity Read ↗

The sensory cilia of Caenorhabditis elegans_RevisedSemantic proximity Read ↗

The Caenorhabditis elegans nephrocystins act as global modifiers of cilium structure.Semantic proximity Read ↗

Primary cilium in kidney development, function and diseaseSemantic proximity Read ↗

Cystic canal mutants in Caenorhabditis elegans are defective in the apical membrane domain of the renal (excretory) cell.Semantic proximity Read ↗

Expression and phenotype analysis of the nephrocystin-1 and nephrocystin-4 homologs in Caenorhabditis elegans.Semantic proximity Read ↗

Functional characterization of the C. elegans nephrocystins NPHP-1 and NPHP-4 and their role in cilia and male sensory behaviors.Semantic proximity Read ↗

Zebrafish kidney development: Basic science to translational researchSemantic proximity Read ↗

Nephronophthisis-Associated CiliopathiesSemantic proximity Read ↗

Renal Pathology of CiliopathiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.