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Article

Evolution of influenza A(H1N1) viruses during a period of low antigenic drift in 1986-91: sequence of the HA1 domain of influenza A/Finland/158/91.

Research in virology - 1 Jan 2000

Kinnunen L, Ikonen N, Pöyry T, Pyhälä R

Abstract excerpt

This study used the nucleotide sequence coding for the HA1 domain of virus haemagglutinin to show that influenza A/Finland/158/91, which represents the H1N1 subtype viruses prevalent in Finland in 1990/91, was a direct descendant of a virus (A/NN/1605/88) isolated during the 1988/89 epidemic season in Japan. The elevated rate of 7.4 x 10(-3) nucleotide substitutions per site per year is discussed. The new branch...

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Identifiers

PMID: 1565849
DOI: 10.1016/s0923-2516(06)80071-3

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