Article
Polymorphism in the promoter region of the apolipoprotein A5 gene is associated with an increased susceptibility for coronary artery disease.
Atherosclerosis - 1 Mar 2004
Szalai Csaba, Keszei Márton, Duba Jenõ, Prohászka Zoltán, Kozma Gergely Tibor, Császár Albert, Balogh Sándor, Almássy Zsuzsa, Fust George, Czinner Antal
Abstract excerpt
Although triglycerides (TG) are a major risk factor for coronary artery disease (CAD), their exact role is still controversial. Recently, a T/C polymorphism in the promoter region of the apoA5 gene at position 1131 has been found that is associated with an increased plasma TG concentration. We investigated the role of this polymorphism in 308 Hungarian patients with CAD referred to coronary bypass surgery, and in...
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