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Article

Aneuploidy-cancer predisposition syndromes: a new link between the mitotic spindle checkpoint and cancer.

Cell cycle (Georgetown, Tex.) - 1 Feb 2005

Hanks Sandra, Rahman Nazneen

Abstract excerpt

Genetic cancer predisposition syndromes have been crucial to the identification of genes and pathways involved in carcinogenesis. Constitutional gene mutations segregating with distinctive cancer phenotypes provide unequivocal evidence of a gene's causal role in cancer. This type of evidence has been central in proving that oncogenes and tumor suppressor genes can cause human cancers, but has been lacking for...

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PMID: 15655355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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