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Article

Does aneuploidy cause cancer?

Current opinion in cell biology - 1 Dec 2006

Weaver Beth A A, Cleveland Don W

Abstract excerpt

Aneuploidy has been recognized as a common characteristic of cancer cells for >100 years. Aneuploidy frequently results from errors of the mitotic checkpoint, the major cell cycle control mechanism that acts to prevent chromosome missegregation. The mitotic checkpoint is often compromised in human tumors, although not as a result of germline mutations in genes encoding checkpoint proteins. Less obviously,...

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Identifiers

PMID: 17046232
DOI: 10.1016/j.ceb.2006.10.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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