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Article

Phenotype analysis of aquaporin-8 null mice.

American journal of physiology. Cell physiology - 1 May 2005

Yang Baoxue, Song Yuanlin, Zhao Dan, Verkman A S

Abstract excerpt

Aquaporin-8 (AQP8) is a water-transporting protein expressed in organs of the mammalian gastrointestinal tract (salivary gland, liver, pancreas, small intestine, and colon) and in the testes, heart, kidney, and airways. We studied the phenotype of AQP8-null mice, and mice lacking AQP8, together with AQP1 or AQP5. AQP8-knockout mice lacked detectable AQP8 transcript and protein, and had reduced water permeability...

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Source

Identifiers

PMID: 15647389
DOI: 10.1152/ajpcell.00564.2004

Genes

AQP8
AQP1
AQP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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