Article
Changes in the SU can modulate the susceptibility of feline immunodeficiency virus to TM-derived entry inhibitors.
The new microbiologica - 1 Apr 2004
Giannecchini S, Pistello M, Del Santo B, Rovero P, Sichi O, Bendinelli M
Abstract excerpt
Feline immunodeficiency virus (FIV) provides a valuable animal model by which criteria for the development of HIV-1 inhibitors can be explored. Previous studies had shown that a synthetic 8-mer peptide modeled on the tryptophan-rich motif of the ectodomain of the viral transmembrane glycoprotein (TM) is a potent inhibitor of FIV The observation that inhibition efficiency varied somewhat depending on FV strain...
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