Article
The detection of a mutation of CD18 gene in bovine leukocyte adhesion deficiency (BLAD).
The Journal of veterinary medical science - 1 Feb 1993
Tajima M, Irie M, Kirisawa R, Hagiwara K, Kurosawa T, Takahashi K
Abstract excerpt
Two calves (5 and 9 months old) affected with pneumonia and gingivitis were also diagnosed as having bovine leukocyte adhesion deficiency (BLAD). The gene of leukocyte adhesion molecule CD18 in these BLAD calves and their dams (carrier) were examined by means of polymerase chain reaction (PCR) and digestion of restriction endonuclease. The splicing in mRNA coded CD18 reported in human LAD was not recognized in...
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