Article
Production, characterization and evaluation of virulence of an adhesion defective mutant of Flavobacterium columnare produced by beta-lactam selection.
Letters in applied microbiology - 1 Jan 2005
Bader J A, Shoemaker C A, Klesius P H
Abstract excerpt
AIMS: The aim of this study was to develop and evaluate mutants of Flavobacterium columnare, the causative agent of columnaris disease in fish. METHODS AND RESULTS: Serial passage on ampicillin (beta-lactam) enriched modified Hsu-Shotts medium resulted in a F. columnare mutant that differed from the parent strain in colony morphology, whole cell proteins, adhesion and virulence. The mutant differed from its...
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