Article
Development and characterization of rifampicin-resistant mutants from high virulent strains of Flavobacterium columnare.
Journal of fish diseases - 1 May 2011
Olivares-Fuster O, Arias C R
Abstract excerpt
Flavobacterium columnare is divided into three genetic groups or genomovars, genomovar II being highly virulent for channel catfish. A modified live vaccine is currently available to prevent columnaris disease under the licensed name Aquavac-Col(®) . The strain of F. columnare used to generate the avirulent rifampicin-resistant mutant used in Aquavac-Col(®) belonged to genomovar I, the less virulent group towards...
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