Article
A bipartite signal mediates the transfer of type IV secretion substrates of <i>Bartonella henselae</i> into human cells
10 Jan 2005
Abstract excerpt
Bacterial type IV secretion (T4S) systems mediate the transfer of macromolecular substrates into various target cells, e.g., the conjugative transfer of DNA into bacteria or the transfer of virulence proteins into eukaryotic host cells. The T4S apparatus VirB of the vascular tumor-inducing pathogen Bartonella henselae causes subversion of human endothelial cell (HEC) function. Here we report the identification of...
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