Article
Antibodies against cyclic citrullinated peptide are associated with HLA-DR4 in simplex and multiplex polyarticular-onset juvenile rheumatoid arthritis.
Arthritis and rheumatism - 1 Jan 2005
Ferucci Elizabeth D, Majka Darcy S, Parrish Lezlie A, Moroldo Marta B, Ryan Mary, Passo Murray, Thompson Susan D, Deane Kevin D, Rewers Marian, Arend William P, Glass David N, Norris Jill M, Holers V Michael
Abstract excerpt
OBJECTIVE: Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been detected in patients with juvenile rheumatoid arthritis (JRA), particularly in those with polyarticular, rheumatoid factor (RF)-positive JRA. Our objectives were to determine whether anti-CCP antibodies are associated with HLA-DR4 in children with polyarticular JRA, whether anti-CCP antibodies are associated with clinical features of...
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