Article
Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast.
Current biology : CB - 29 Dec 2004
Wilkinson Caroline R M, Dittmar Gunnar A G, Ohi Melanie D, Uetz Peter, Jones Nic, Finley Daniel
Abstract excerpt
Hub1/Ubl5 is a member of the family of ubiquitin-like proteins (UBLs). The tertiary structure of Hub1 is similar to that of ubiquitin; however, it differs from known modifiers in that there is no conserved glycine residue near the C terminus which, in ubiquitin and UBLs, is required for covalent modification of target proteins. Instead, there is a conserved dityrosine motif proximal to the terminal nonconserved...
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