Article
Experimental traumatic brain injury modulates the survival, migration, and terminal phenotype of transplanted epidermal growth factor receptor-activated neural stem cells.
Neurosurgery - 1 Jan 2005
Boockvar John A, Schouten Joost, Royo Nicolas, Millard Marie, Spangler Zak, Castelbuono Debbie, Snyder Evan, O'Rourke Donald, McIntosh Tracy
Abstract excerpt
OBJECTIVE: We have previously shown that constitutively active epidermal growth factor receptor signaling enhances the survival and motility of engrafted neural stem cells (NSCs) when transplanted into normal adult brain. In the present study, using the C17.2 NSC line stably transfected with the constitutively active epidermal growth factor receptor vIII, we sought to evaluate the phenotype of NSCs after...
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