Article
Evaluation of Downstream Regulatory Element Antagonistic Modulator Gene in Human Multinodular Goiter.
Medical science monitor basic research - 30 Aug 2015
Shinzato Amanda, Lerario Antonio M, Lin Chin J, Danilovic Debora S, Marui Suemi, Trarbach Ericka B
Abstract excerpt
BACKGROUND DREAM (Downstream Regulatory Element Antagonistic Modulator) is a neuronal calcium sensor that was suggested to modulate TSH receptor activity and whose overexpression provokes an enlargement of the thyroid gland in transgenic mice. The aim of this study was to investigate somatic muta...
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