Article
INK4-ARF and p53 mutations in metastatic cutaneous squamous cell carcinoma: case report and archival study on the use of Ink4a-ARF and p53 mutation analysis in identification of the corresponding primary tumor.
The American journal of surgical pathology - 1 Jan 2005
Blokx Willeke A M, Ruiter Dirk J, Verdijk Marian A J, de Wilde Peter C M, Willems Riki W, de Jong Elke M G J, Ligtenberg Marjolijn J L
Abstract excerpt
So far, histopathologic, immunohistochemical and molecular properties of metastatic cutaneous squamous cell carcinomas (CSCCs) are relatively unexplored. In patients with multiple CSCCs, as for instance renal transplant recipients (RTRs), it might prove difficult to identify the primary tumor responsible for metastasis. We report a case of an RTR with multiple CSCCs, one of which metastasized. By using p53 and...
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