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Article

Transformation of Madin-Darby Canine Kidney Epithelial Cells by Sheep Retrovirus Envelope Proteins

21 Dec 2004

Abstract excerpt

Jaagsiekte sheep retrovirus (JSRV) and enzootic nasal tumor virus (ENTV) induce epithelial tumors in the airways of sheep and goats. In both of these simple retroviruses, the envelope (Env) protein is the active oncogene. Furthermore, JSRV Env can transform cultured cells by two distinct mechanisms. In rat and mouse fibroblasts, the cytoplasmic tail of JSRV Env is essential for transformation, which involves...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 15613321
DOI: 10.1128/jvi.79.2.927-933.2005

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Transformation of Madin-Darby Canine Kidney Epithelial Cells by Sheep Retrovirus Envelope ProteinsPMID 15613321Read ↗

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