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Article

Transformation and oncogenesis by jaagsiekte sheep retrovirus.

Current topics in microbiology and immunology - 1 Jan 2003

Fan H, Palmarini M, DeMartini J C

Abstract excerpt

Jaagsiekte sheep retrovirus (JSRV) is an exogenous retrovirus of sheep that induces a contagious lung cancer, ovine pulmonary adenocarcinoma (OPA). JSRV is a potent carcinogen in the experimental setting, inducing end-stage tumors at around 6 weeks of age when newborn lambs are inoculated intratracheally. Despite this rapid oncogenesis, inspection of the JSRV genome sequence does not reveal any obvious viral...

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PMID: 12596898
DOI: 10.1007/978-3-642-55638-8_6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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