Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The spindle assembly checkpoint is not essential for CSF arrest of mouse oocytes.

The Journal of cell biology - 20 Dec 2004

Tsurumi Chizuko, Hoffmann Steffen, Geley Stephan, Graeser Ralph, Polanski Zbigniew

Abstract excerpt

In Xenopus oocytes, the spindle assembly checkpoint (SAC) kinase Bub1 is required for cytostatic factor (CSF)-induced metaphase arrest in meiosis II. To investigate whether matured mouse oocytes are kept in metaphase by a SAC-mediated inhibition of the anaphase-promoting complex/cyclosome (APC/C)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaphase-Promoting Complex-Cyclosome
Share to Mad2 Proteins
Share to Meiosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred Strains

Share to Nocodazole

Share to Oocytes

Share to Spindle Apparatus

Share to Ubiquitin-Protein Ligase Complexes

Source

Open in PubMed Open full text

Identifiers

PMID: 15611331
DOI: 10.1083/jcb.200405165
PMCID: PMC2172623

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15611331-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The spindle assembly checkpoint is not essential for CSF arrest of mouse oocytes.PMID 15611331Read ↗

The spindle checkpoint kinase bub1 and cyclin e/cdk2 both contribute to the establishment of meiotic metaphase arrest by cytostatic factor.Semantic proximity Read ↗

Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor-mediated metaphase arrest.Semantic proximity Read ↗

Changing Mad2 Levels Affects Chromosome Segregation and Spindle Assembly Checkpoint Control in Female Mouse Meiosis ISemantic proximity Read ↗

Mad2 is dispensable for accurate chromosome segregation but becomes essential when oocytes are subjected to environmental stressSemantic proximity Read ↗

CDC6 requirement for spindle formation during maturation of mouse oocytes.Semantic proximity Read ↗

Cyclin B3 promotes anaphase I onset in oocyte meiosisSemantic proximity Read ↗

Spindle assembly checkpoint regulates mitotic cell cycle progression during preimplantation embryo development.Semantic proximity Read ↗

Cyclin B3 promotes APC/C activation and anaphase I onset in oocyte meiosisSemantic proximity Read ↗

Smc1β is required for activation of SAC during mouse oocyte meiosisSemantic proximity Read ↗

DNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpointSemantic proximity Read ↗

Evidence That a Defective Spindle Assembly Checkpoint Is Not the Primary Cause of Maternal Age-Associated Aneuploidy in Mouse Eggs1Semantic proximity Read ↗

BRCA1 Is Required for Meiotic Spindle Assembly and Spindle Assembly Checkpoint Activation in Mouse Oocytes1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.