Patterns of sequence divergence in 5' intergenic spacers and linked coding regions in 10 species of pathogenic bacteria reveal distinct recombinational histories.

doi:10.1534/genetics.104.032979

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Article

Patterns of sequence divergence in 5' intergenic spacers and linked coding regions in 10 species of pathogenic bacteria reveal distinct recombinational histories.

Genetics - 1 Dec 2004

Hughes Austin L, Friedman Robert

Abstract excerpt

We compared the pattern of nucleotide difference in 8034 genes and in their 5' intergenic spacers between conspecific pairs of genomes from 10 species of pathogenic bacteria. Certain genes or spacers showed much greater sequence divergence between the genotypes compared to others; such divergent regions plausibly originated by recombinational events by which a gene and/or spacers was donated from a divergent...

Topics

Bacteria
Base Sequence
DNA, Intergenic
Evolution, Molecular
Gene Frequency
Genetic Variation
Promoter Regions, Genetic
Recombination, Genetic
Streptococcus agalactiae

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Identifiers

PMID: 15611157
DOI: 10.1534/genetics.104.032979
PMCID: PMC1448726

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