Article
Genetic diversity of the obligate intracellular bacterium Chlamydophila pneumoniae by genome-wide analysis of single nucleotide polymorphisms: evidence for highly clonal population structure.
BMC genomics - 4 Oct 2007
Rattei Thomas, Ott Stephan, Gutacker Michaela, Rupp Jan, Maass Matthias, Schreiber Stefan, Solbach Werner, Wirth Thierry, Gieffers Jens
Abstract excerpt
BACKGROUND: Chlamydophila pneumoniae is an obligate intracellular bacterium that replicates in a biphasic life cycle within eukaryotic host cells. Four published genomes revealed an identity of > 99 %. This remarkable finding raised questions about the existence of distinguishable genotypes in correlation with geographical and anatomical origin. RESULTS: We studied the genetic diversity of C. pneumoniae by...
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