Article
Small variable segments constitute a major type of diversity of bacterial genomes at the species level.
Genome biology - 1 Jan 2010
Touzain Fabrice, Denamur Erick, Médigue Claudine, Barbe Valérie, El Karoui Meriem, Petit Marie-Agnès
Abstract excerpt
BACKGROUND: Analysis of large scale diversity in bacterial genomes has mainly focused on elements such as pathogenicity islands, or more generally, genomic islands. These comprise numerous genes and confer important phenotypes, which are present or absent depending on strains. We report that despite this widely accepted notion, most diversity at the species level is composed of much smaller DNA segments, 20 to...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA, Bacterial
- Escherichia coli
- Genetic Variation
- Genome, Bacterial
- Molecular Sequence Data
- Species Specificity
- Staphylococcus aureus
- Streptococcus pyogenes