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Article

Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1.

The Journal of biological chemistry - 4 Mar 2005

Lux Andreas, Beil Christian, Majety Meher, Barron Suzanne, Gallione Carol J, Kuhn Hella-Monika, Berg Jonathan N, Kioschis Petra, Marchuk Douglas A, Hafner Mathias

Abstract excerpt

Mutations in activin receptor-like kinase 1 (ALK1), a transforming growth factor (TGF)-beta type I receptor, lead to the vascular disorder hereditary hemorrhagic telangiectasia caused by abnormal vascular remodeling. The underlying molecular cause of this disease is not well understood. Identifying binding partners for ALK1 will help to understand its cellular function. Using the two-hybrid system, we identified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15611116
DOI: 10.1074/jbc.M409197200

Genes

PEG10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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