Article
Caveolin-1 as a prime modulator of aging: a new modality for phenotypic restoration?
Mechanisms of ageing and development - 1 Jan 2005
Cho Kyung A, Park Sang Chul
Abstract excerpt
Aging can be characterized by structural changes and functional deterioration during the lifetime, for which hundreds of explanations have been put forward. Recently, we have proposed the gate theory of aging, in which gatekeeper molecules at the membrane level would play the prime role in determining the senescent phenotype. Caveolin-1 would be a prime candidate for such a role as a major determinant of the...
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