Article
The expression of iASPP in acute leukemias.
Leukemia research - 1 Feb 2005
Zhang Xinwei, Wang Min, Zhou Chunlin, Chen Sen, Wang Jianxiang
Abstract excerpt
Inhibitory member of the ASPP family (iASPP) is an evolutionarily conserved inhibitor of p53, and its expression is upregulated in human breast carcinomas expressing wild-type p53. To examine the role of iASPP in acute leukemia (AL), we analyzed iASPP mRNA expression in AL by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR). PCR products were confirmed by restriction endonuclease BstX I...
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