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Article

Artesunate-dapsone-proguanil treatment of falciparum malaria: genotypic determinants of therapeutic response.

Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Feb 2005

Krudsood Sivicha, Imwong Mallika, Wilairatana Polrat, Pukrittayakamee Sasithon, Nonprasert Apichart, Snounou Georges, White Nicholas J, Looareesuwan Sornchai

Abstract excerpt

The combination of chlorproguanil and dapsone is being considered as an alternative antimalarial to sulfadoxine-pyrimethamine in Africa, because of its greater efficacy against resistant parasites, and its shorter half-lives, which exert less selective pressure for the emergence of resistance. A triple artesunate-chlorproguanil-dapsone combination is under development. In a previous study of relatively low-dose...

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Identifiers

PMID: 15607340
DOI: 10.1016/j.trstmh.2004.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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