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Article

Sickle cell disease: old discoveries, new concepts, and future promise.

The Journal of clinical investigation - 1 Apr 2007

Frenette Paul S, Atweh George F

Abstract excerpt

The discovery of the molecular basis of sickle cell disease was an important landmark in molecular medicine. The modern tools of molecular and cellular biology have refined our understanding of its pathophysiology and facilitated the development of new therapies. In this review, we discuss some of the important advances in this field and the impediments that limit the impact of these advances.

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Identifiers

PMID: 17404610
DOI: 10.1172/JCI30920
PMCID: PMC1838946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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