Article
Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Dec 2004
Roumier Anne, Béchade Catherine, Poncer Jean-Christophe, Smalla Karl-Heinz, Tomasello Elena, Vivier Eric, Gundelfinger Eckart D, Triller Antoine, Bessis Alain
Abstract excerpt
Several proteins are expressed in both immune and nervous systems. However, their putative nonimmune functions in the brain remain poorly understood. KARAP/DAP12 is a transmembrane polypeptide associated with cell-surface receptors in hematopoeitic cells. Its mutation in humans induces Nasu-Hakol...
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