Article
Association between the risk for lung adenocarcinoma and a (-4) G-to-A polymorphism in the XPA gene.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2004
Butkiewicz Dorota, Popanda Odilia, Risch Angela, Edler Lutz, Dienemann Hendrik, Schulz Volker, Kayser Klaus, Drings Peter, Bartsch Helmut, Schmezer Peter
Abstract excerpt
Polymorphisms of genes coding for DNA repair can affect lung cancer risk. A common single nucleotide (-4) G-to-A polymorphism was identified previously in the 5' untranslated region of the XPA gene. In a case-control study in European Caucasians, the influence of this polymorphism on primary lung cancer risk overall and according to histologic subtypes was investigated. Four hundred sixty-three lung cancer cases...
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