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Article

Novel testis-expressed profilin IV associated with acrosome biogenesis and spermatid elongation

1 Jan 2005

Abstract excerpt

A novel profilin, named profilin IV, was cloned and characterized as a testicular isoform, distinct from the previously described testis-specific profilin III. Profilin IV showed only 30% amino acid identity with the other mammalian profilins; nevertheless, database searches produced significant alignments with the conserved profilin domain. Northern blot analysis and in situ transcript hybridization suggested...

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PMID: 15591451
DOI: 10.1093/molehr/gah132

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