Yellow fever virus isolated from a fatal post vaccination event: an experimental comparative study with the 17DD vaccine strain in the Syrian hamster (Mesocricetus auratus).

doi:10.1590/s0037-86822004000700011

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Article

Yellow fever virus isolated from a fatal post vaccination event: an experimental comparative study with the 17DD vaccine strain in the Syrian hamster (Mesocricetus auratus).

Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2004

Rodrigues Sueli Guerreiro, da Rosa Amélia Paes de Andrade Travassos, Galler Ricardo, Barros Vera Lúcia Reis de Souza, Vieira Conceição de Maria Almeida, da Rosa Jorge Fernando Soares Travassos, Azevedo Raimunda do Socorro da Silva, Nunes Márcio Roberto Teixeira, da Rosa Elizabeth Salbé Travassos, Vasconcelos Pedro Fernando da Costa

Abstract excerpt

In order to investigate the pathogenicity of the virus strain GOI 4191 that was isolated from a fatal adverse event after yellow fever virus (YFV) vaccination, an experimental assay using hamsters (Mesocricetus auratus) as animal model and YFV 17DD vaccine strain as virus reference was accomplished. The two virus strains were inoculated by intracerebral, intrahepatic and subcutaneous routes. The levels of...

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PMID: 15586900
DOI: 10.1590/s0037-86822004000700011

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