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Article

Genetic analysis of diverse disease-causing pneumococci indicates high levels of diversity within serotypes and capsule switching.

Journal of clinical microbiology - 1 Dec 2004

Jefferies Johanna M C, Smith Andrew, Clarke Stuart C, Dowson Chris, Mitchell Timothy J

Abstract excerpt

We have used multilocus sequence typing (MLST) and serotyping to build a phylogenetic framework for pneumococcal disease isolates in Scotland that provides a snapshot of the relationships between capsular type and genotype. The results show that while the MLST type correlates with the serotype, isolates within a serotype can belong to a number of individual clonal complexes or sequence types (STs). We also show...

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Identifiers

PMID: 15583299
DOI: 10.1128/JCM.42.12.5681-5688.2004
PMCID: PMC535294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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