Article
Genomic diversity between strains of the same serotype and multilocus sequence type among pneumococcal clinical isolates.
Infection and immunity - 1 Jun 2006
Silva Nuno A, McCluskey Jackie, Jefferies Johanna M C, Hinds Jason, Smith Andrew, Clarke Stuart C, Mitchell Tim J, Paterson Gavin K
Abstract excerpt
The important human pathogen Streptococcus pneumoniae is known to be a genetically diverse species. We have used comparative genome hybridization (CGH) microarray analysis to investigate this diversity in a collection of clinical isolates including several capsule serotype 14 pneumococci, a dominant serotype among disease isolates. We have identified three new regions of diversity among pneumococcal isolates and,...
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