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Article

Correlation between clinical characteristics and mitochondrial D-loop DNA mutations in hepatocellular carcinoma.

Journal of gastroenterology - 1 Nov 2004

Tamori Akihiro, Nishiguchi Shuhei, Nishikawa Manabu, Kubo Shoji, Koh Noritoshi, Hirohashi Kazuhiro, Shiomi Susumu, Inoue Masayasu

Abstract excerpt

BACKGROUND: Mitochondrial DNA (mtDNA) mutations are found in many kinds of human cancer. The aim of this study was to evaluate the relationship between mtDNA mutations in the liver and human hepatocarcinogenesis. METHODS: Direct sequencing of mtDNA was done in 54 hepatocellular carcinomas (HCCs) and 47 surrounding liver tissue samples, obtained from 54 patients with HCC, and in 5 liver samples without...

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Share to Carcinoma, Hepatocellular
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Liver Neoplasms

Share to Mitochondrial Function and Pathology

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Share to Polymerase Chain Reaction

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 15580399
DOI: 10.1007/s00535-004-1445-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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