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Article

Cytochrome c oxidase deficiency.

American journal of medical genetics - 1 Jan 2001

Shoubridge E A

Abstract excerpt

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain, catalyzing the transfer of electrons from reduced cytochrome c to molecular oxygen. It is composed of 13 structural subunits, three of which are encoded in mtDNA and form the catalytic core of the enzyme. In addition to these structural subunits, a large number of accessory factors are necessary for the assembly and...

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Source

Identifiers

PMID: 11579424
DOI: 10.1002/ajmg.1378

Genes

COX10
SCO1
SCO2
SURF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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