Article
Diminished response to activated protein C is not correlated with severity of peripheral arterial occlusive disease.
Clinical laboratory - 1 Jan 2004
Köppel H, Renner W, Krippl P, Wascher T C, Pilger E
Abstract excerpt
INTRODUCTION: Poor response to activated Protein C (APC) is a well established risk factor for venous thromboembolism. More recently, the hypercoagulable state which results from diminished response to APC has also been associated with arterial thrombosis. Some studies showed a clear association between low response to APC with advanced arterial disease, others, however, failed to support these data. Thus, there...
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