Article
Human Rhesus-associated glycoprotein mediates facilitated transport of NH(3) into red blood cells.
Proceedings of the National Academy of Sciences of the United States of America - 7 Dec 2004
Ripoche Pierre, Bertrand Olivier, Gane Pierre, Birkenmeier Connie, Colin Yves, Cartron Jean-Pierre
Abstract excerpt
Rhesus (Rh) antigens are carried by a membrane complex that includes Rh proteins (D and CcEe), Rh-associated glycoproteins (RhAG), and accessory chains (LW and CD47) associated by noncovalent bonds. In heterologous expression systems, RhAG and its kidney orthologs function as ammonium transporters. In red blood cells (RBCs), it is generally accepted that NH(3) permeates by membrane lipid diffusion. We have...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
