Article
A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae.
The Journal of biological chemistry - 11 Feb 2005
Shimazu Masamitsu, Sekito Takayuki, Akiyama Koichi, Ohsumi Yoshinori, Kakinuma Yoshimi
Abstract excerpt
Among the members of the major facilitator superfamily of Saccharomyces cerevisiae, we identified genes involved in the transport into vacuoles of the basic amino acids histidine, lysine, and arginine. ATP-dependent uptake of histidine and lysine by isolated vacuolar membrane vesicles was impaired in YMR088c, a vacuolar basic amino acid transporter 1 (VBA1)-deleted strain, whereas uptake of tyrosine or calcium...
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