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Article

The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line.

Developmental biology - 1 Jan 2005

Kozlowski David J, Whitfield Tanya T, Hukriede Neil A, Lam Wai K, Weinberg Eric S

Abstract excerpt

To understand the molecular basis of sensory organ development and disease, we have cloned and characterized the zebrafish mutation dog-eared (dog) that is defective in formation of the inner ear and lateral line sensory systems. The dog locus encodes the eyes absent-1 (eya1) gene and single point mutations were found in three independent dog alleles, each prematurely truncating the expressed protein within the...

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Identifiers

PMID: 15572137
DOI: 10.1016/j.ydbio.2004.08.033

Genes

EYA1
EYA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line.PMID 15572137Read ↗

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