Article
Glutathione sulfur transferase M1 and T1 genotypes in chronic lymphoblastic leukemia.
The hematology journal : the official journal of the European Haematology Association - 1 Jan 2004
Tsabouri Sophia, Georgiou Ioannis, Katsaraki Afroditi, Bourantas Kostantinos Lambros
Abstract excerpt
Glutathione sulfur transferases (GSTs) is a group of enzymes involved in the detoxification process of carcinogens and other substances. The genes encoding isoenzymes M1 and T1 are polymorphic in humans and the phenotypic absence of enzyme activity (null genotype) may have an effect on the risk of chronic lymphoblastic leukemia (CLL). Our purpose was to examine whether the GSTM1 and GSTT1 homozygous null...
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