Article
Effects of energy balance on cancer in genetically altered mice.
The Journal of nutrition - 1 Dec 2004
Patel Arti C, Nunez Nomeli P, Perkins Susan N, Barrett J Carl, Hursting Stephen D
Abstract excerpt
Evidence has accumulated from laboratory-based animal experiments and population-based human epidemiological studies that lifestyle factors that affect energy balance, such as caloric intake, nutritional status, and exercise, act in concert with genetic susceptibility to influence cancer development and progression. The use of animal models with specific genetic alterations, in combination with lifestyle...
Topics
- Alleles
- Animals
- Energy Intake
- Energy Metabolism
- Female
- Genes, APC
- Genes, p53
- Genetic Predisposition to Disease
- Heterozygote
- Humans
- Insulin-Like Growth Factor I
- Life Style
- Male
- Mice
- Mice, Knockout
- Mice, Transgenic
- Mutation
- Neoplasms
