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Article

MSH receptors in immortalized human epidermal keratinocytes: A potential mechanism for coordinate regulation of the epidermal‐melanin unit

1 Nov 1993

Abstract excerpt

Receptors for melanotropin (MSH) were found to be expressed by immortalized primary human epidermal keratinocytes (RHEK-1). Using 125I-beta MSH as a probe, the MSH receptors from mouse melanoma cells and human keratinocytes were found to be remarkably similar. In each cell line, there were high and low affinity receptors, with the high affinity classes showing positive cooperativity. Competition of 125I-beta MSH...

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PMID: 8227166
DOI: 10.1002/jcp.1041570218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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