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Article

Gastric cancer originating from bone marrow-derived cells.

Science (New York, N.Y.) - 26 Nov 2004

Houghton Jeanmarie, Stoicov Calin, Nomura Sachiyo, Rogers Arlin B, Carlson Jane, Li Hanchen, Cai Xun, Fox James G, Goldenring James R, Wang Timothy C

Abstract excerpt

Epithelial cancers are believed to originate from transformation of tissue stem cells. However, bone marrow-derived cells (BMDCs), which are frequently recruited to sites of tissue injury and inflammation, might also represent a potential source of malignancy. We show that although acute injury, acute inflammation, or transient parietal cell loss within the stomach do not lead to BMDC recruitment, chronic...

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Identifiers

PMID: 15567866
DOI: 10.1126/science.1099513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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