Article
Factor XI mutation in a Holstein cow with repeat breeding in Japan.
The Journal of veterinary medical science - 1 Jul 2005
Ghanem Mohamed Elshabrawy, Nishibori Masahide, Nakao Toshihiko, Nakatani Keiji, Akita Masashi
Abstract excerpt
Factor XI deficiency is an autosomal recessive coagulopathy in Holstein cattle. Affected cows have a tendency to show repeat breeding. Forty repeat breeding Holstein Friesian cows were selected and tested for the Factor XI mutation. Genomic DNA was isolated from the blood of the cows (n=40). Exon 12 of the Factor XI gene of the cows was amplified by PCR. One repeat breeding cow was heterozygous to the Factor XI...
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