Article
Interaction at a distance between multiple operators controls the adjacent, divergently transcribed glpTQ-glpACB operons of Escherichia coli K-12.
The Journal of biological chemistry - 25 Mar 1992
Larson T J, Cantwell J S, van Loo-Bhattacharya A T
Abstract excerpt
The glp regulon of Escherichia coli encodes the proteins required for utilization of sn-glycerol 3-phosphate and its precursors. Transcription of the divergently transcribed glpTQ and glpACB operons is initiated at sites separated by 132 base pairs (bp) of DNA. These operons are controlled negatively by glp repressor and positively by the cAMP-cAMP receptor protein (CRP) complex. The locations of the binding...
Topics
- Base Sequence
- Binding Sites
- Cloning, Molecular
- DNA, Bacterial
- Deoxyribonuclease I
- Escherichia coli
- Genetic Variation
- Glycerophosphates
- Models, Biological
- Molecular Sequence Data