Article
Characterization of DNA-binding specificity and analysis of binding sites of the Pseudomonas aeruginosa global regulator, Vfr, a homologue of the Escherichia coli cAMP receptor protein.
Microbiology (Reading, England) - 1 Dec 2006
Kanack Kristen J, Runyen-Janecky Laura J, Ferrell Evan P, Suh Sang-Jin, West Susan E H
Abstract excerpt
Vfr, a global regulator of Pseudomonas aeruginosa virulence factors, is a homologue of the Escherichia coli cAMP receptor protein, CRP. Vfr is 91% similar to CRP and maintains many residues important for CRP to bind cAMP, bind DNA, and interact with RNA polymerase at target promoters. While vfr can complement an E. coli crp mutant in beta-galactosidase production, tryptophanase production and catabolite...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.