Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stimulation of transcriptional expression of human UDP-glucuronosyltransferase 1A1 by dexamethasone.

Molecular biology reports - 1 Sept 2004

Kanou Masanobu, Usui Toru, Ueyama Hisao, Sato Hiroshi, Ohkubo Iwao, Mizutani Takaharu

Abstract excerpt

Human UDP-glucuronosyltransferase (UGT) 1A1 is only enzyme in the conjugation of bilirubin for prevention of hyperbilirubinemia and jaundice. Deletion or mutation of the UGT1A1 gene causes Crigler-Najjar syndrome or Gilbert's syndrome. We previously reported the functional promoter region for expression of UGT1A1 [Hepatology Research 9, 152-163 (1997)]. We investigated the influence of some drugs on the transient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bilirubin
Share to Dexamethasone
Share to Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estradiol

Share to Genes, Reporter

Share to Glucocorticoids

Share to Glucuronosyltransferase

Share to Luciferases

Source

Identifiers

PMID: 15560369
DOI: 10.1023/b:mole.0000043582.35335.ff

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stimulation of transcriptional expression of human UDP-glucuronosyltransferase 1A1 by dexamethasone.PMID 15560369Read ↗

Function, Genetic Polymorphism, and Transcriptional Regulation of Human UDP-glucuronosyltransferase (UGT) 1A1Semantic proximity Read ↗

The role of Ah receptor in induction of human UDP-glucuronosyltransferase 1A1.Semantic proximity Read ↗

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.Semantic proximity Read ↗

Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells.Semantic proximity Read ↗

Regulation of human glucocorticoid receptor gene transcription by Sp1 and p53.Semantic proximity Read ↗

Molecular pathogenesis of Gilbert's syndrome: decreased TATA-binding protein binding affinity of UGT1A1 gene promoterSemantic proximity Read ↗

Tissue-specific, Inducible, and Hormonal Control of the Human UDP-Glucuronosyltransferase-1 (UGT1) LocusSemantic proximity Read ↗

Glucocorticoid Stimulates Hepatitis B Viral Gene Expression in Cultured Human Hepatoma CellsSemantic proximity Read ↗

Genetic polymorphisms in the TATA box and upstream phenobarbital-responsive enhancer module of the UGT1A1 promoter have combined effects on UDP-glucuronosyltransferase 1A1 transcription mediated by constitutive androstane receptor, pregnane X receptor, or glucocorticoid receptor in human liver.Semantic proximity Read ↗

Characterization of cis-elements mediating the stimulation of glucose-6-phosphate transporter promoter activity by glucocorticoids.Semantic proximity Read ↗

Human beta-fibrinogen gene expression. Upstream sequences involved in its tissue specific expression and its dexamethasone and interleukin 6 stimulation.Semantic proximity Read ↗

Induction of UGT1A6 isoform by inflammatory conditions in rat astrocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.