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Article

Novel algorithm for automated genotyping of microsatellites.

Nucleic acids research - 1 Jan 2004

Matsumoto Toshiko, Yukawa Wataru, Nozaki Yasuyuki, Nakashige Ryo, Shinya Minori, Makino Satoshi, Yagura Masaru, Ikuta Tomoki, Imanishi Tadashi, Inoko Hidetoshi, Tamiya Gen, Gojobori Takashi

Abstract excerpt

Microsatellites or short tandem repeats (STRs) are abundant in the human genome with easily assayed polymorphisms, providing powerful genetic tools for mapping both Mendelian and complex traits. Microsatellite genotyping requires detection of the products of polymerase chain reaction (PCR) amplification by electrophoresis, and analysis of the peak data for discrimination of the true allele. A high-throughput...

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PMID: 15557284
DOI: 10.1093/nar/gkh946
PMCID: PMC534627

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