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Article

The leucine regulon of Escherichia coli K-12: a mutation in rblA alters expression of L-leucine-dependent metabolic operons.

Journal of bacteriology - 1 Aug 1990

Tuan L R, D'Ari R, Newman E B

Abstract excerpt

We have isolated and characterized a highly pleiotropic Escherichia coli mutant affected in the activity of a number of enzymes involved in different metabolic pathways, all of which are regulated by leucine. Selected for its ability to grow with L-serine as sole carbon source, the rbl-1::Tn10 mutant had high levels of L-serine deaminase activity (due to increased transcription of the structural gene) and of...

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Identifiers

PMID: 2165479
DOI: 10.1128/jb.172.8.4529-4535.1990
PMCID: PMC213284

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