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Article

The leucine regulon of Escherichia coli K-12: a mutation in rblA alters expression of L-leucine-dependent metabolic operons.

Journal of bacteriology - 1 Aug 1990

Tuan L R, D'Ari R, Newman E B

Abstract excerpt

We have isolated and characterized a highly pleiotropic Escherichia coli mutant affected in the activity of a number of enzymes involved in different metabolic pathways, all of which are regulated by leucine. Selected for its ability to grow with L-serine as sole carbon source, the rbl-1::Tn10 mu...

Topics

Alcohol Oxidoreductases
DNA Transposable Elements
Escherichia coli
Genes, Regulator
Genotype
L-Serine Dehydratase
Leucine
Methionine Adenosyltransferase
Mutation
Operon
Transcription, Genetic
beta-Galactosidase

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Identifiers

PMID: 2165479
DOI: 10.1128/jb.172.8.4529-4535.1990
PMCID: PMC213284

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2165479-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The leucine regulon of Escherichia coli K-12: a mutation in rblA alters expression of L-leucine-dependent metabolic operons.PMID 2165479Read ↗

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