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Article

Cardiac involvement in patients with lamin A/C gene mutations: a cohort observation.

Muscle & nerve - 1 Aug 2012

Carboni Nicola, Sardu Claudia, Cocco Eleonora, Marrosu Giovanni, Manzi Rosa C, Nissardi Vincenzo, Isola Franco, Mateddu Anna, Solla Elisabetta, Maioli Maria A, Oppo Valentina, Piras Rachele, Coghe Giancarlo, Lai Carlo, Marrosu Maria G

Abstract excerpt

INTRODUCTION: LMNA gene mutations are associated with cardiac and skeletal muscle alterations. METHODS: A cohort of 21 mutated individuals was assessed with clinical and instrumental investigations over the years. RESULTS: The median observation period was 6 years. Cardiac compromise was detected in 16 patients. Bradyarrhythmias were the most frequent manifestations, followed by supraventricular arrhythmias. Two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22806367
DOI: 10.1002/mus.23294

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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